Sexual Problems in Human Males Exposed to High BPA Levels

Wednesday, August 18, 2010

Barely one week after Consumer Reports found unexpectedly high levels of the chemical Bisphenol A (BPA) in name-brand food products, a federally-financed study says the substance appears to cause erectile dysfunction and other sexual problems in men. A study released last month linked exposure to BPA during pregnancy to hyperactivity and aggression in girls.

BPA, a synthetic version of estrogen, is used in everything from plastic baby bottles to canned food linings and has been detected in the urine of 93 percent of the U.S. population. It has been linked to a wide array of health effects including reproductive abnormalities, heightened risk of breast and prostate cancers, diabetes, and heart disease.

The latest study, published in the journal Human Reproduction, was conducted on male workers at four factories in China, is the first to study the effects of BPA on human males. Previous studies have used mice and rats, a point often seized upon by industry-backed critics who have claimed there is no evidence of ill effects on humans.

"Critics dismissed all the animal studies," said De-Kun Li of the Kaiser Foundation Research Institute, which conducted the study with funding from the National Institute for Occupational Safety and Health, The Washington Post reported. "Now we have a human study and this can't just be dismissed."

Nevertheless, the American Chemistry Council (ACC) -- which represents the chemical industry -- was quick to discount the findings.

“This study of occupational exposure to bisphenol A (BPA) among male factory workers in China provides interesting new information, although its relevance to average consumers who use products containing minute amounts of BPA is limited, at best," said Steven G. Hentges, Ph.D., of the ACC's Polycarbonate/BPA Global Group. "Based on the significant differences between occupational exposure and consumer exposure, the study’s authors state, ‘the findings from this study probably do not apply to populations that are exposed to low levels of BPA.’" he noted.

600 workers

Researchers followed more than 600 workers over a five-year period and compared their sexual well-being with that of male workers in other Chinese plants where no BPA was present. They found that men handling BPA were four times as likely to suffer from erectile dysfunction and seven times as likely to have difficulty ejaculating.

Researchers said they did not have to wait long to see the results of BPA exposure. Within just a few months of starting to work at the factories, the study's subjects began to develop sexual dysfunction.

While exposure levels in the Chinese group were as much as 50 times what an average U.S. male faces, Li said the findings nevertheless raise questions about the safety of exposure at lesser levels.

The National Institutes of Health (NIH) last week said it would spend $30 million to examine the safety of BPA and the U.S. Food and Drug Administration (FDA) is expected to release its own findings from an ongoing study within the next month.

A recent EPA study found that exposure to low levels of BPA had no effect on a range of reproductive and behavioral activities measured. But the FDA's scientific advisory board has cited more than 100 studies linking BPA with health effects and the Obama administration has pressed agencies to take a "fresh look" at the issue.

FDA panel

An FDA special scientific advisory panel reported in late 2008 that the agency's basis for setting safety standards to protect consumers was inadequate and should be reevaluated. A congressional subcommittee determined in 2009 that the agency relied too heavily on studies sponsored by the American Plastics Council. The FDA, now under the leadership of Dr. Margaret Hamburg, is expected to announce soon its reassessment of BPA safety. Bills are currently pending in Congress that would ban the use of BPA in all food and beverage containers.

Consumers who are concerned might be able to reduce, though not necessarily eliminate, their dietary exposure to BPA by taking the following steps:

• Choose fresh food whenever possible.

• Consider alternatives to canned food, beverages, juices, and infant formula.

• Use glass containers when heating food in microwave ovens.



By Truman Lewis
ConsumerAffairs

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